Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription.

Xeroderma pigmentosum (XP) is a rare hereditary human disorder clinically associated with severe sun sensitivity and predisposition to skin cancer. Some XP patients also show clinical characteristics of Cockayne syndrome (CS), a disorder associated with defective preferential repair of DNA lesions i...

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Λεπτομέρειες βιβλιογραφικής εγγραφής
Εκδόθηκε σε:	Nucleic Acids Res
Κύριοι συγγραφείς:	van Hoffen, A, Kalle, W H, de Jong-Versteeg, A, Lehmann, A R, van Zeeland, A A, Mullenders, L H
Μορφή:	Artigo
Γλώσσα:	Inglês
Έκδοση:	Oxford University Press 1999
Θέματα:	Research Article
Διαθέσιμο Online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148504/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10390531/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.14.2898
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Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription.

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