Cells from XP-D and XP-D-CS patients exhibit equally inefficient repair of UV-induced damage in transcribed genes but different capacity to recover UV-inhibited transcription.

Xeroderma pigmentosum (XP) is a rare hereditary human disorder clinically associated with severe sun sensitivity and predisposition to skin cancer. Some XP patients also show clinical characteristics of Cockayne syndrome (CS), a disorder associated with defective preferential repair of DNA lesions i...

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Bibliographische Detailangaben
Hauptverfasser: van Hoffen, A, Kalle, W H, de Jong-Versteeg, A, Lehmann, A R, van Zeeland, A A, Mullenders, L H
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1999
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC148504/
https://ncbi.nlm.nih.gov/pubmed/10390531
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