Long 5' leaders inhibit removal of a 3' trailer from a precursor tRNA by mammalian tRNA 3' processing endoribonuclease.

Mammalian tRNA 3' processing endoribonuclease (3' tRNase) can remove a 3' trailer from various pre-tRNAs without 5' leader nucleotides. To examine how 5[prime] leader sequences affect 3' processing efficiency, we performed in vitro 3' processing reactions with purified...

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Main Authors: Nashimoto, M, Wesemann, D R, Geary, S, Tamura, M, Kaspar, R L
Formáid: Artigo
Teanga:Inglês
Foilsithe: 1999
Ábhair:
Research Article
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC148487/
https://ncbi.nlm.nih.gov/pubmed/10373595
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