Long 5' leaders inhibit removal of a 3' trailer from a precursor tRNA by mammalian tRNA 3' processing endoribonuclease.

Mammalian tRNA 3' processing endoribonuclease (3' tRNase) can remove a 3' trailer from various pre-tRNAs without 5' leader nucleotides. To examine how 5[prime] leader sequences affect 3' processing efficiency, we performed in vitro 3' processing reactions with purified pig 3' tRNase and pre-tRNAArgs...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Nashimoto, M, Wesemann, D R, Geary, S, Tamura, M, Kaspar, R L
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1999
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148487/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373595/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.13.2770
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