Bioactivity of anti-angiogenic ribozymes targeting Flt-1 and KDR mRNA.
Vascular endothelial growth factor (VEGF) and its receptors Flt-1 and KDR play important roles in physiological and pathological angiogenesis. Ribozymes that target the VEGF receptor mRNAs were developed and their biological activities in cell culture and an animal model were assessed. Ribozymes tar...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148463/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10373571/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.13.2569 |
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