Determinants of nucleotide sugar recognition in an archaeon DNA polymerase.

Vent DNA polymerase normally discriminates strongly against incorporation of ribonucleotides, 3'-deoxyribonucleotides (such as cordycepin) and 2',3'-dideoxyribonucleotides. To explore the basis for this discrimination we have generated a family of variants with point mutations of residues in conserv...

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Pubblicato in:	Nucleic Acids Res
Autori principali:	Gardner, A F, Jack, W E
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Oxford University Press 1999
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10352184/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.12.2545
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