Determinants of nucleotide sugar recognition in an archaeon DNA polymerase.
Vent DNA polymerase normally discriminates strongly against incorporation of ribonucleotides, 3'-deoxyribonucleotides (such as cordycepin) and 2',3'-dideoxyribonucleotides. To explore the basis for this discrimination we have generated a family of variants with point mutations of residues in conserv...
Zapisane w:
| Wydane w: | Nucleic Acids Res |
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| Główni autorzy: | , |
| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Oxford University Press
1999
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148459/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10352184/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.12.2545 |
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