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Naive CD4 T cells constitutively express CD40L and augment autoreactive B cell survival
Chronic engagement of the B cell receptor by soluble autoantigen leads to reduced B cell survival. Using the Ig and hen egg lysozyme double transgenic mouse model, we demonstrate that the survival of soluble autoantigen-engaged B cells is further reduced in mice lacking CD4 T cells or deficient in C...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
National Academy of Sciences
2006
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1484418/ https://ncbi.nlm.nih.gov/pubmed/16815973 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0601539103 |
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