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ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein

Degradative fragments of cartilage oligomeric matrix protein (COMP) have been observed in arthritic patients. The physiological enzyme(s) that degrade COMP, however, remain unknown. We performed a yeast two-hybrid screen (Y2H) to search for proteins that associate with COMP to identify an interactio...

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Bibliografske podrobnosti
Main Authors: Liu, Chuan-ju, Kong, Wei, Ilalov, Kiril, Yu, Shuang, Xu, Ke, Prazak, Lisa, Fajardo, Marc, Sehgal, Bantoo, Di Cesare, Paul E.
Format: Artigo
Jezik:Inglês
Izdano: 2006
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483927/
https://ncbi.nlm.nih.gov/pubmed/16585064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.05-3877fje
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