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ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein

Degradative fragments of cartilage oligomeric matrix protein (COMP) have been observed in arthritic patients. The physiological enzyme(s) that degrade COMP, however, remain unknown. We performed a yeast two-hybrid screen (Y2H) to search for proteins that associate with COMP to identify an interactio...

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Detalhes bibliográficos
Main Authors: Liu, Chuan-ju, Kong, Wei, Ilalov, Kiril, Yu, Shuang, Xu, Ke, Prazak, Lisa, Fajardo, Marc, Sehgal, Bantoo, Di Cesare, Paul E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2006
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483927/
https://ncbi.nlm.nih.gov/pubmed/16585064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.05-3877fje
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