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ADAMTS-7: a metalloproteinase that directly binds to and degrades cartilage oligomeric matrix protein

Degradative fragments of cartilage oligomeric matrix protein (COMP) have been observed in arthritic patients. The physiological enzyme(s) that degrade COMP, however, remain unknown. We performed a yeast two-hybrid screen (Y2H) to search for proteins that associate with COMP to identify an interactio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Chuan-ju, Kong, Wei, Ilalov, Kiril, Yu, Shuang, Xu, Ke, Prazak, Lisa, Fajardo, Marc, Sehgal, Bantoo, Di Cesare, Paul E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1483927/
https://ncbi.nlm.nih.gov/pubmed/16585064
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.05-3877fje
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