Nalaganje...
Barminomycin forms GC-specific adducts and virtual interstrand crosslinks with DNA.
The sequence specificity of the binding of barminomycin (SN-07 chromophore) to DNA was investigated using an in vitro transcription assay. It was found that this compound formed blockages to transcription, and these blocks were highly selective for 5'-GC sequences. The half-lives of the first s...
Shranjeno v:
| Main Authors: | , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
1999
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC148384/ https://ncbi.nlm.nih.gov/pubmed/10101184 |
| Oznake: |
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