Use of an internal ribosome entry site for bicistronic expression of Cre recombinase or rtTA transactivator.
Conditional gene targeting depends on tissue and time specificity of recombination events. Endogenous promoters are often used to drive various transgenic constructs. To avoid the problems associated with reconstituting a specific expression pattern in transgenic animals by this method, we tested th...
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| Опубликовано в:: | Nucleic Acids Res |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Oxford University Press
1999
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10037820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.6.1552 |
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