Use of an internal ribosome entry site for bicistronic expression of Cre recombinase or rtTA transactivator.
Conditional gene targeting depends on tissue and time specificity of recombination events. Endogenous promoters are often used to drive various transgenic constructs. To avoid the problems associated with reconstituting a specific expression pattern in transgenic animals by this method, we tested th...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1999
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148352/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10037820/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.6.1552 |
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