Smoothing of the thermal stability of DNA duplexes by using modified nucleosides and chaotropic agents.

The effect of alkyltrimethylammonium ions on the thermostability of natural and modified DNA duplexes has been investigated. We have shown that the use of tetramethylammonium ions TMA+along with the chemical modification of duplexes allow the fine adjustment of T m and the possibility of obtaining s...

Fuld beskrivelse

Bibliografiske detaljer

Udgivet i:	Nucleic Acids Res
Principais autores:	Nguyen, H K, Fournier, O, Asseline, U, Dupret, D, Thuong, N T
Format:	Artigo
Sprog:	Inglês
Udgivet:	Oxford University Press 1999
Fag:	Research Article
Online adgang:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148343/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10037811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.6.1492
Tags:	Tilføj Tag Ingen Tags, Vær først til at tagge denne postø!