Smoothing of the thermal stability of DNA duplexes by using modified nucleosides and chaotropic agents.
The effect of alkyltrimethylammonium ions on the thermostability of natural and modified DNA duplexes has been investigated. We have shown that the use of tetramethylammonium ions TMA+along with the chemical modification of duplexes allow the fine adjustment of T m and the possibility of obtaining s...
Guardat en:
| Publicat a: | Nucleic Acids Res |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Oxford University Press
1999
|
| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148343/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10037811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.6.1492 |
| Etiquetes: |
Sense etiquetes, Sigues el primer a etiquetar aquest registre!
|