Smoothing of the thermal stability of DNA duplexes by using modified nucleosides and chaotropic agents.

The effect of alkyltrimethylammonium ions on the thermostability of natural and modified DNA duplexes has been investigated. We have shown that the use of tetramethylammonium ions TMA+along with the chemical modification of duplexes allow the fine adjustment of T m and the possibility of obtaining s...

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Bibliografski detalji

Izdano u:	Nucleic Acids Res
Glavni autori:	Nguyen, H K, Fournier, O, Asseline, U, Dupret, D, Thuong, N T
Format:	Artigo
Jezik:	Inglês
Izdano:	Oxford University Press 1999
Teme:	Research Article
Online pristup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148343/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10037811/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.6.1492
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