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Base pairing of anhydrohexitol nucleosides with 2,6-diaminopurine, 5-methylcytosine and uracil asbase moiety.

Hexitol nucleic acids (HNAs) with modified bases (5-methylcytosine, 2,6-diaminopurine or uracil) were synthesized. The introduction of the 5-methylcytosine base demonstrates that N -benzoylated 5-methylcytosyl-hexitol occurs as the imino tautomer. The base pairing systems (G:CMe, U:D, T:D and U:A) o...

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Detalhes bibliográficos
Main Authors: Boudou, V, Kerremans, L, De Bouvere, B, Lescrinier, E, Schepers, G, Busson, R, Van Aerschot, A, Herdewijn, P
Formato: Artigo
Idioma:Inglês
Publicado em: 1999
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC148337/
https://ncbi.nlm.nih.gov/pubmed/10037805
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