Transforming Growth Factor β(1) Selectively Inhibits the Cyclic AMP-dependent Proliferation of Primary Thyroid Epithelial Cells by Preventing the Association of Cyclin D3–cdk4 with Nuclear p27(kip1)

Dog thyroid epithelial cells in primary culture constitute a physiologically relevant model of positive control of DNA synthesis initiation and G0-S prereplicative phase progression by cAMP as a second messenger for thyrotropin (thyroid-stimulating hormone [TSH]). As previously shown in this system,...

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Hauptverfasser: Depoortere, Fabienne, Pirson, Isabelle, Bartek, Jiri, Dumont, Jacques E., Roger, Pierre P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2000
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC14831/
https://ncbi.nlm.nih.gov/pubmed/10712520
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