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Aneugenic Activity of Op18/Stathmin Is Potentiated by the Somatic Q18→E Mutation in Leukemic Cells
Op18/stathmin (Op18) is a phosphorylation-regulated microtubule destabilizer that is frequently overexpressed in tumors. The importance of Op18 in malignancy was recently suggested by identification of a somatic Q18→E mutation of Op18 in an adenocarcinoma. We addressed the functional consequences of...
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| Hlavní autoři: | , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
The American Society for Cell Biology
2006
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1483029/ https://ncbi.nlm.nih.gov/pubmed/16624860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-02-0165 |
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