Trif-related adapter molecule is phosphorylated by PKCε during Toll-like receptor 4 signaling

PKCε has been shown to play a key role in the effect of the Gram-negative bacterial product LPS; however, the target for PKCε in LPS signaling is unknown. LPS signaling is mediated by Toll-like receptor 4, which uses four adapter proteins, MyD88, MyD88 adapter-like (Mal), Toll/IL-1R domain-containin...

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Autores principales: McGettrick, Anne F., Brint, Elizabeth K., Palsson-McDermott, Eva M., Rowe, Daniel C., Golenbock, Douglas T., Gay, Nicholas J., Fitzgerald, Katherine A., O'Neill, Luke A. J.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2006
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482589/
https://ncbi.nlm.nih.gov/pubmed/16757566
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0600462103
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