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Processes of copy-number change in human DNA: The dynamics of α-globin gene deletion

Ectopic recombination between locally repeated DNA sequences is of fundamental importance in the evolution of gene families, generating copy-number variation in human DNA and often leading to pathological rearrangements. Despite its importance, little is known about the dynamics and processes of the...

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書目詳細資料
Main Authors: Lam, Kwan-Wood G., Jeffreys, Alec J.
格式: Artigo
語言:Inglês
出版: National Academy of Sciences 2006
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC1482541/
https://ncbi.nlm.nih.gov/pubmed/16709669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602690103
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