Functional analysis of human MutSalpha and MutSbeta complexes in yeast.
Mismatch repair (MMR) is initiated when a heterodimer of hMSH2*hMSH6 or hMSH2*hMSH3 binds to mismatches. Here we perform functional analyses of these human protein complexes in yeast. We use a sensitive genetic system wherein the rate of single-base deletions in a homopolymeric run in the LYS2 gene...
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| Pubblicato in: | Nucleic Acids Res |
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| Autori principali: | , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
1999
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148241/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9889267/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.3.736 |
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