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Immobilization of acrylamide-modified oligonucleotides by co-polymerization.

A flexible chemistry for solid phase attachment of oligonucleotides is described. Oligonucleotides bearing 5'-terminal acrylamide modifications efficiently co-polymerize with acrylamide monomers to form thermally stable DNA-containing polyacrylamide co-polymers. Co-polymerization attachment is speci...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:Nucleic Acids Res
Hauptverfasser: Rehman, F N, Audeh, M, Abrams, E S, Hammond, P W, Kenney, M, Boles, T C
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 1999
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148228/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9862993/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/27.2.649
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