Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages

BACKGROUND: The major risk factor for the development of COPD is cigarette smoking. Smoking causes activation of resident cells and the recruitment of inflammatory cells into the lungs, which leads to release of pro-inflammatory cytokines, chemotactic factors, oxygen radicals and proteases. In the p...

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Detalhes bibliográficos
Main Authors: Karimi, Khalil, Sarir, Hadi, Mortaz, Esmaeil, Smit, Joost J, Hosseini, Hossein, De Kimpe, Sjef J, Nijkamp, Frans P, Folkerts, Gert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2006
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481582/
https://ncbi.nlm.nih.gov/pubmed/16620395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-66
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