Cigarette smoke regulates the expression of TLR4 and IL-8 production by human macrophages

BACKGROUND: Toll-like receptors (TLRs) are present on monocytes and alveolar macrophages that form the first line of defense against inhaled particles. The importance of those cells in the pathophysiology of chronic obstructive pulmonary disease (COPD) has well been documented. Cigarette smoke conta...

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Detalhes bibliográficos
Main Authors: Sarir, Hadi, Mortaz, Esmaeil, Karimi, Khalil, Kraneveld, Aletta D, Rahman, Irfan, Caldenhoven, Eric, Nijkamp, Frans P, Folkerts, Gert
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2009
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2683828/
https://ncbi.nlm.nih.gov/pubmed/19409098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-9255-6-12
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