Toll-like receptor-4 mediates cigarette smoke-induced cytokine production by human macrophages

BACKGROUND: The major risk factor for the development of COPD is cigarette smoking. Smoking causes activation of resident cells and the recruitment of inflammatory cells into the lungs, which leads to release of pro-inflammatory cytokines, chemotactic factors, oxygen radicals and proteases. In the p...

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Hlavní autoři: Karimi, Khalil, Sarir, Hadi, Mortaz, Esmaeil, Smit, Joost J, Hosseini, Hossein, De Kimpe, Sjef J, Nijkamp, Frans P, Folkerts, Gert
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2006
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1481582/
https://ncbi.nlm.nih.gov/pubmed/16620395
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1465-9921-7-66
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