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Directed Reduction of β-Amino Ketones to Syn or Anti 1,3-Amino Alcohol Derivatives

[Image: see text] The reduction of β-amino ketones with samarium(II) iodide has been investigated. Either the syn or anti 1,3-amino alcohols can be obtained as the major product due to a divergence in selectivity with different N-protecting groups.

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Detalhes bibliográficos
Main Authors: Keck, Gary E., Truong, Anh P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1480404/
https://ncbi.nlm.nih.gov/pubmed/12201734
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