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Directed Reduction of β-Amino Ketones to Syn or Anti 1,3-Amino Alcohol Derivatives
[Image: see text] The reduction of β-amino ketones with samarium(II) iodide has been investigated. Either the syn or anti 1,3-amino alcohols can be obtained as the major product due to a divergence in selectivity with different N-protecting groups.
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Main Authors: | , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2002
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1480404/ https://ncbi.nlm.nih.gov/pubmed/12201734 |
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