Cationic porphyrins: novel delivery vehicles for antisense oligodeoxynucleotides.

Cationic porphyrins form stable complexes with oligodeoxynucleotides. To evaluate delivery, we used a 20mer phosphorothioate oligomer (Isis 3521) targeted to the 3'-untranslated region of the PKC-alpha mRNA, and complexed it with porphyrin. The expression of PKC-alpha protein and mRNA in T24 bladder...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Benimetskaya, L, Takle, G B, Vilenchik, M, Lebedeva, I, Miller, P, Stein, C A
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148008/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.23.5310
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