Cationic porphyrins: novel delivery vehicles for antisense oligodeoxynucleotides.
Cationic porphyrins form stable complexes with oligodeoxynucleotides. To evaluate delivery, we used a 20mer phosphorothioate oligomer (Isis 3521) targeted to the 3'-untranslated region of the PKC-alpha mRNA, and complexed it with porphyrin. The expression of PKC-alpha protein and mRNA in T24 bladder...
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| Yayımlandı: | Nucleic Acids Res |
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| Asıl Yazarlar: | , , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
Oxford University Press
1998
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC148008/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826753/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.23.5310 |
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