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At least three linear regions but not the zinc-finger domain of U1C protein are exposed at the surface of the protein in solution and on the human spliceosomal U1 snRNP particle.

No structural information on U1C protein either in its free state or bound to the spliceosomal U1 small nuclear ribonucleoprotein (snRNP) particle is currently available. Using rabbit antibodies raised against a complete set of 15 U1C overlapping synthetic peptides (16-30 residues long) in different...

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Bibliografiske detaljer
Main Authors: Dumortier, H, Klein Gunnewiek, J, Roussel, J P, van Aarssen, Y, Briand, J P, van Venrooij, W J, Muller, S
Format: Artigo
Sprog:Inglês
Udgivet: 1998
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC147990/
https://ncbi.nlm.nih.gov/pubmed/9826776
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