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Characterization of different isoforms of the HIF prolyl hydroxylase PHD1 generated by alternative initiation
The heterodimeric transcription factor HIF (hypoxia-inducible factor) is central to the regulation of gene expression by oxygen. Three oxygen-dependent prolyl hydroxylase enzymes [PHD1 (prolyl hydroxylase domain 1), PHD2 and PHD3] control the abundance of HIF. In the presence of oxygen, they hydroxy...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Portland Press Ltd.
2006
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1479752/ https://ncbi.nlm.nih.gov/pubmed/16509823 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20051996 |
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