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Restoration of tissue factor pathway inhibitor (TFPI) inhibits invasion and tumor growth in vitro and in vivo in a malignant meningioma cell line
Tissue factor pathway inhibitor 2 (TFPI-2) is a 32 kDa extracellular matrix-associated kunitz-type serine proteinase inhibitor. It is secreted by all vascular cells and plays a role in tumor invasion and metastasis, presumably by plasmin-mediated matrix remodeling. Previous studies have shown high e...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1479607/ https://ncbi.nlm.nih.gov/pubmed/16773181 |
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