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Decreased expression of topoisomerase IIbeta in poly(ADP-ribose) polymerase-deficient cells.

Recent studies with poly(ADP-ribose) polymerase (PARP)-deficient mice have highlighted the role of this enzyme in genomic stability and response to various genomic insults. In the absence of DNA damaging treatment, we report here that a PARP-deficient cell line (PARP-/-) established from knockout mi...

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Detalhes bibliográficos
Main Authors: Canitrot, Y, de Murcia, G, Salles, B
Formato: Artigo
Idioma:Inglês
Publicado em: 1998
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC147949/
https://ncbi.nlm.nih.gov/pubmed/9801310
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