The IL-21 receptor augments Th2 effector function and alternative macrophage activation

The IL-21 receptor (IL-21R) shows significant homology with the IL-4R, and CD4(+) Th2 cells are an important source of IL-21. Here we examined whether the IL-21R regulates the development of Th2 responses in vivo. To do this, we infected IL-21R(–/–) mice with the Th2-inducing pathogens Schistosoma m...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Pesce, John, Kaviratne, Mallika, Ramalingam, Thirumalai R., Thompson, Robert W., Urban, Joseph F., Cheever, Allen W., Young, Deborah A., Collins, Mary, Grusby, Michael J., Wynn, Thomas A.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2006
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479424/
https://ncbi.nlm.nih.gov/pubmed/16778988
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI27727
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados