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Immunoglobulin A Antibodies against Ricin A and B Subunits Protect Epithelial Cells from Ricin Intoxication

Epithelial cells of the respiratory and gastrointestinal tracts are extremely vulnerable to the cytotoxic effects of ricin, a Shiga-like toxin with ribosome-inactivating properties. While mucosal immunity to ricin correlates with secretory immunoglobulin A (IgA) antibody levels in vivo, the potentia...

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Autori principali: Mantis, Nicholas J., McGuinness, Carolyn R., Sonuyi, Oluwakemi, Edwards, Gary, Farrant, Stephanie A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479255/
https://ncbi.nlm.nih.gov/pubmed/16714576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.02088-05
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