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A Humanized Monoclonal Antibody Cocktail to Prevent Pulmonary Ricin Intoxication

PB10 IgG(1), a monoclonal antibody (MAb) directed against an immunodominant epitope on the enzymatic subunit (RTA) of ricin toxin (RT), has been shown to passively protect mice and non-human primates from an aerosolized lethal-dose RT challenge. However, it was recently demonstrated that the therape...

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Podrobná bibliografie
Vydáno v:Toxins (Basel)
Hlavní autoři: Rong, Yinghui, Pauly, Michael, Guthals, Adrian, Pham, Henry, Ehrbar, Dylan, Zeitlin, Larry, Mantis, Nicholas J.
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232472/
https://ncbi.nlm.nih.gov/pubmed/32235318
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/toxins12040215
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