Urea improves efficiency of bisulphite-mediated sequencing of 5'-methylcytosine in genomic DNA.
The detection of 5'-methylcytosine by the bisulphite-mediated genomic sequencing method has considerably aided study of the role of methylation in areas such as X chromosome inactivation, genomic imprinting and cancer research. However on occasion difficulty has been experienced in obtaining complet...
保存先:
| 出版年: | Nucleic Acids Res |
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| 主要な著者: | , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Oxford University Press
1998
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147923/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9776768/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.21.5009 |
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