Synthesis and physical characterization of DNA fragments containing N4-methylcytosine and 5-methylcytosine.

The synthesis of N4-methyl-2'-deoxycytidine and its fully protected mononucleotide, suitable for the oligonucleotide synthesis by phosphotriester method is described. A set of octanucleotides - d(CGCGCGCG), d(CG5mCGCGCG), d(CG4mCGCGCG) and dodecanucleotides - d(GGACCCGGGTCC), d(GGA5mCCCGGGTCC),...

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Main Authors: Butkus, V, Klimasauskas, S, Petrauskiene, L, Maneliene, Z, Janulaitis, A, Minchenkova, L E, Schyolkina, A K
Formato: Artigo
Idioma:Inglês
Publicado: 1987
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC306371/
https://ncbi.nlm.nih.gov/pubmed/3671089
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