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Mechanism of Enhanced Activity of Liposome-Entrapped Aminoglycosides against Resistant Strains of Pseudomonas aeruginosa

Pseudomonas aeruginosa is inherently resistant to most conventional antibiotics. The mechanism of resistance of this bacterium is mainly associated with the low permeability of its outer membrane to these agents. We sought to assess the bactericidal efficacy of liposome-entrapped aminoglycosides aga...

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Detalhes bibliográficos
Main Authors: Mugabe, Clement, Halwani, Majed, Azghani, Ali O., Lafrenie, Robert M., Omri, Abdelwahab
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479138/
https://ncbi.nlm.nih.gov/pubmed/16723560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01547-05
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