Activity and Interactions of Liposomal Antibiotics in Presence of Polyanions and Sputum of Patients with Cystic Fibrosis

BACKGROUND: To compare the effectiveness of liposomal tobramycin or polymyxin B against Pseudomonas aeruginosa in the Cystic Fibrosis (CF) sputum and its inhibition by common polyanionic components such as DNA, F-actin, lipopolysaccharides (LPS), and lipoteichoic acid (LTA). METHODOLOGY: Liposomal f...

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Bibliographic Details
Main Authors: Alipour, Misagh, Suntres, Zacharias E., Halwani, Majed, Azghani, Ali O., Omri, Abdelwahab
Format: Artigo
Language:Inglês
Published: Public Library of Science 2009
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2685033/
https://ncbi.nlm.nih.gov/pubmed/19479000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0005724
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