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Mechanism of Enhanced Activity of Liposome-Entrapped Aminoglycosides against Resistant Strains of Pseudomonas aeruginosa

Pseudomonas aeruginosa is inherently resistant to most conventional antibiotics. The mechanism of resistance of this bacterium is mainly associated with the low permeability of its outer membrane to these agents. We sought to assess the bactericidal efficacy of liposome-entrapped aminoglycosides aga...

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Bibliographische Detailangaben
Hauptverfasser: Mugabe, Clement, Halwani, Majed, Azghani, Ali O., Lafrenie, Robert M., Omri, Abdelwahab
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2006
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479138/
https://ncbi.nlm.nih.gov/pubmed/16723560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01547-05
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