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Kinetic Definition of Protein Folding Transition State Ensembles and Reaction Coordinates

Using distributed molecular dynamics simulations we located four distinct folding transitions for a 39-residue ββαβ protein fold. To characterize the nature of each room temperature transition, we calculated the probability of transmission for 500 points along each free energy barrier. We introduced...

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Bibliografiska uppgifter
Huvudupphovsmän: Snow, Christopher D., Rhee, Young Min, Pande, Vijay S.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Biophysical Society 2006
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479057/
https://ncbi.nlm.nih.gov/pubmed/16617068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.105.075689
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