Nuclear mRNA Degradation Pathway(s) Are Implicated in Xist Regulation and X Chromosome Inactivation

A critical step in X-chromosome inactivation (XCI), which results in the dosage compensation of X-linked gene expression in mammals, is the coating of the presumptive inactive X chromosome by the large noncoding Xist RNA, which then leads to the recruitment of other factors essential for the heteroc...

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Detaylı Bibliyografya
Asıl Yazarlar: Ciaudo, Constance, Bourdet, Agnès, Cohen-Tannoudji, Michel, Dietz, Harry C, Rougeulle, Claire, Avner, Philip
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Public Library of Science 2006
Konular:
Research Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC1479048/
https://ncbi.nlm.nih.gov/pubmed/16789828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.0020094
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