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Repair of DNA strand gaps and nicks containing 3'-phosphate and 5'-hydroxyl termini by purified mammalian enzymes.

A putative role for mammalian polynucleotide kinases that possess both 5'-phosphotransferase and 3'-phosphatase activity is the restoration of DNA strand breaks with 5'-hydroxyl termini or 3'-phosphate termini, or both, to a form that supports the subsequent action of DNA repair...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Karimi-Busheri, F, Lee, J, Tomkinson, A E, Weinfeld, M
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1998
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC147863/
https://ncbi.nlm.nih.gov/pubmed/9742240
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