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Repair of DNA strand gaps and nicks containing 3'-phosphate and 5'-hydroxyl termini by purified mammalian enzymes.

A putative role for mammalian polynucleotide kinases that possess both 5'-phosphotransferase and 3'-phosphatase activity is the restoration of DNA strand breaks with 5'-hydroxyl termini or 3'-phosphate termini, or both, to a form that supports the subsequent action of DNA repair polymerases and DNA...

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Udgivet i:Nucleic Acids Res
Principais autores: Karimi-Busheri, F, Lee, J, Tomkinson, A E, Weinfeld, M
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 1998
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147863/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9742240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.19.4395
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