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Crystal structures of VAP1 reveal ADAMs' MDC domain architecture and its unique C-shaped scaffold
ADAMs (a disintegrin and metalloproteinase) are sheddases possessing extracellular metalloproteinase/disintegrin/cysteine-rich (MDC) domains. ADAMs uniquely display both proteolytic and adhesive activities on the cell surface, however, most of their physiological targets and adhesion mechanisms rema...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2006
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1478178/ https://ncbi.nlm.nih.gov/pubmed/16688218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601131 |
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