A chimeric Cre recombinase inducible by synthetic,but not by natural ligands of the glucocorticoid receptor.
We have developed a new ligand-dependent chimeric recombinase (Cre-GRdex) by fusing the site-specific Cre recombinase to the ligand binding domain (LBD) of a mutant human glucocorticoid receptor (GRdex). The synthetic glucocorticoid receptor (GR) ligands dexamethasone, triamcinolone acetonide and RU...
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| 發表在: | Nucleic Acids Res |
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| Principais autores: | , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Oxford University Press
1998
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9705523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.17.4086 |
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