A chimeric Cre recombinase inducible by synthetic,but not by natural ligands of the glucocorticoid receptor.

We have developed a new ligand-dependent chimeric recombinase (Cre-GRdex) by fusing the site-specific Cre recombinase to the ligand binding domain (LBD) of a mutant human glucocorticoid receptor (GRdex). The synthetic glucocorticoid receptor (GR) ligands dexamethasone, triamcinolone acetonide and RU...

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Detalhes bibliográficos

Publicado no:	Nucleic Acids Res
Principais autores:	Brocard, J, Feil, R, Chambon, P, Metzger, D
Formato:	Artigo
Idioma:	Inglês
Publicado em:	Oxford University Press 1998
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147795/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9705523/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.17.4086
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