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Trading the micro-world of combinatorial complexity for the macro-world of protein interaction domains.

Membrane receptors and proteins involved in signal transduction display numerous binding domains and operate as molecular scaffolds generating a variety of parallel reactions and protein complexes. The resulting combinatorial explosion of the number of feasible chemical species and, hence, different...

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Hlavní autoři: Borisov, Nikolay M., Markevich, Nick I., Hoek, Jan B., Kholodenko, Boris N.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2005
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1477537/
https://ncbi.nlm.nih.gov/pubmed/16242235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biosystems.2005.03.006
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