Structure and function of the human Werner syndrome gene promoter: evidence for transcriptional modulation.
The Werner syndrome (WS) is an autosomal recessive segmental progeroid syndrome caused by mutations in a novel member ( WRN ) of the RecQ family of helicases. Somatic WS cells are hypermutable and have elongated S phases, suggesting possible defects in DNA replication and/or repair. As an initial ap...
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| Publicado no: | Nucleic Acids Res |
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| Principais autores: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
1998
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC147734/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9671808/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/26.15.3480 |
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